Interazioni tra farmaci
Atracurium + Oxytetracycline
Gravità: Moderata
Atracurium and Oxytetracycline: moderate interaction.
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Sintesi
Tetracyclines have weak neuromuscular blocking effects, and potentiation of nondepolarising blockers is described mainly in case reports. Clinical significance with oxytetracycline is likely small but could prolong recovery.
Cosa significa questa interazione in parole semplici
Atracurium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atracurium belongs to Musculoskeletal; Oxytetracycline belongs to Anti Bacterial.
Perché avviene
Possible calcium chelation and weak presynaptic neuromuscular blockade adding to nondepolarising blockade.
Cosa fare
Monitor neuromuscular function with train-of-four during surgery or ICU use. Adjust atracurium dosing to response.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Atracurium
- Amikacin + Atracurium Maggiore
- Atracurium + Bacitracin-neomycin-polymyxin Maggiore
- Atracurium + Benzhydrocodone / acetaminophen Maggiore
- Atracurium + Capreomycin Maggiore
- Atracurium + Clindamycin Maggiore
- Atracurium + Colistin Maggiore
Altre interazioni di Oxytetracycline
- Isotretinoin + Oxytetracycline Controindicata
- Aluminum hydroxide + Oxytetracycline Moderata
- Ampicillin-sulbactam + Oxytetracycline Moderata
- Ampicillin + Oxytetracycline Moderata
- Bismuth subsalicylate + Oxytetracycline Moderata
- Calcium carbonate + Oxytetracycline Moderata
Domande frequenti
Can I take Atracurium with Oxytetracycline?
MediHelp rates the interaction as moderate. Atracurium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetracyclines have weak neuromuscular blocking effects, and potentiation of nondepolarising blockers is described mainly in case reports. Clinical significance with oxytetracycline is likely small but could prolong recovery.
How serious is the interaction between Atracurium and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with train-of-four during surgery or ICU use. Adjust atracurium dosing to response.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Atracurium page.
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