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Interazioni tra farmaci

Cangrelor + Warfarin

Gravità: Moderata

Cangrelor and Warfarin: moderate interaction.

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Sintesi

Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.

Cosa significa questa interazione in parole semplici

Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cangrelor belongs to Cardiovascular; Warfarin belongs to Cardiovascular.

Livello di evidenza: Moderate

Perché avviene

Additive pharmacodynamic effect of P2Y12 platelet inhibition and vitamin K antagonist anticoagulation.

Cosa fare

Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Cangrelor with Warfarin?

MediHelp rates the interaction as moderate. Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.

How serious is the interaction between Cangrelor and Warfarin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.

What other medicines interact with Warfarin?

MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.

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