Interazioni tra farmaci
Carbamazepine + Ensitrelvir
Gravità: Controindicata
Carbamazepine and Ensitrelvir: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Carbamazepine is expected to reduce ensitrelvir concentrations substantially, which may lead to loss of antiviral activity and resistance. Strong CYP3A inducers are contraindicated with ensitrelvir.
Cosa significa questa interazione in parole semplici
Carbamazepine and Ensitrelvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Carbamazepine belongs to Central Nervous System; Ensitrelvir belongs to Anti Virals.
Perché avviene
Carbamazepine induces CYP3A4, accelerating ensitrelvir metabolism.
Cosa fare
Avoid the combination and choose an alternative COVID-19 therapy or a non-inducing antiseizure drug. Do not stop carbamazepine abruptly without specialist advice.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Ensitrelvir
- Apalutamide + Ensitrelvir Controindicata
- Colchicine + Ensitrelvir Controindicata
- Ensitrelvir + Enzalutamide Controindicata
- Ensitrelvir + Eplerenone Controindicata
- Ensitrelvir + Finerenone Controindicata
- Ensitrelvir + Ivabradine Controindicata
Altre interazioni di Carbamazepine
- Artemether / lumefantrine + Carbamazepine Controindicata
- Cabotegravir + Carbamazepine Controindicata
- Carbamazepine + Delamanid Controindicata
- Carbamazepine + Dienogest / estradiol valerate Controindicata
- Carbamazepine + Doravirine Controindicata
- Carbamazepine + Elbasvir / grazoprevir Controindicata
Domande frequenti
Can I take Carbamazepine with Ensitrelvir?
MediHelp rates the interaction as contraindicated. Carbamazepine and Ensitrelvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Carbamazepine is expected to reduce ensitrelvir concentrations substantially, which may lead to loss of antiviral activity and resistance. Strong CYP3A inducers are contraindicated with ensitrelvir.
How serious is the interaction between Carbamazepine and Ensitrelvir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose an alternative COVID-19 therapy or a non-inducing antiseizure drug. Do not stop carbamazepine abruptly without specialist advice.
What other medicines interact with Ensitrelvir?
MediHelp also lists interactions of Ensitrelvir with, for example, Apalutamide, Colchicine, Enzalutamide. The full list is on the Ensitrelvir page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
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