Interazioni tra farmaci
Cefotaxime + Cholera vaccine
Gravità: Moderata
Cefotaxime and Cholera vaccine: moderate interaction.
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Sintesi
The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response.
Cosa significa questa interazione in parole semplici
Cefotaxime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Antibacterial activity may inhibit replication of the live attenuated vaccine strain, lowering immunogenicity.
Cosa fare
Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefotaxime
- Cefotaxime + Typhoid vaccine live Maggiore
- Amikacin + Cefotaxime Moderata
- Cefotaxime + Dexamethasone-tobramycin Moderata
- Cefotaxime + Gentamicin Moderata
- Cefotaxime + Kanamycin Moderata
- Cefotaxime + Microbiota Moderata
Domande frequenti
Can I take Cefotaxime with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefotaxime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response.
How serious is the interaction between Cefotaxime and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
What other medicines interact with Cefotaxime?
MediHelp also lists interactions of Cefotaxime with, for example, Typhoid vaccine live, Amikacin, Dexamethasone-tobramycin. The full list is on the Cefotaxime page.
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