Vai al contenuto

Interazioni tra farmaci

Cidofovir + Polymyxin b

Gravità: Controindicata

Cidofovir and Polymyxin b: contraindicated interaction.

Ultimo aggiornamento

Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.

Il contenuto clinico di questa pagina è disponibile solo in inglese.

Sintesi

Both drugs injure the renal tubules, and polymyxin B also has neurotoxic effects. Concurrent use greatly increases the risk of acute kidney injury.

Cosa significa questa interazione in parole semplici

Cidofovir and Polymyxin b are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Cidofovir belongs to Anti Virals; Polymyxin b belongs to Anti Bacterial.

Livello di evidenza: Moderate

Perché avviene

Additive direct tubular nephrotoxicity.

Cosa fare

Avoid the combination, as cidofovir labeling prohibits concurrent nephrotoxins. Use an alternative antibiotic or antiviral, and if unavoidable, monitor creatinine daily.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Per gli utenti Pro+

Sblocca la pagina completa

Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Cidofovir e Polymyxin b, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.

Domande frequenti

Can I take Cidofovir with Polymyxin b?

MediHelp rates the interaction as contraindicated. Cidofovir and Polymyxin b are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs injure the renal tubules, and polymyxin B also has neurotoxic effects. Concurrent use greatly increases the risk of acute kidney injury.

How serious is the interaction between Cidofovir and Polymyxin b?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination, as cidofovir labeling prohibits concurrent nephrotoxins. Use an alternative antibiotic or antiviral, and if unavoidable, monitor creatinine daily.

What other medicines interact with Cidofovir?

MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.

Monografie complete, posologie e verifica delle interazioni nell'app MediHelp

Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.

Sfoglia dalla A alla Z · Interazioni tra farmaci

Scarica l'app Accedi