Interazioni tra farmaci
Copper + Trientine
Gravità: Moderata
Copper and Trientine: moderate interaction.
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Sintesi
Trientine chelates copper and promotes its elimination, which is the intended therapeutic effect in Wilson's disease. Copper supplementation would oppose this, and excessive treatment can cause copper deficiency.
Cosa significa questa interazione in parole semplici
Copper and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Trientine belongs to Miscellaneous.
Perché avviene
Trientine chelates copper, increasing urinary excretion and limiting absorption.
Cosa fare
Avoid copper supplements in patients treated with trientine for Wilson's disease. Monitor serum and urinary copper and watch for over-treatment such as anemia.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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- Evidence detail
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Altre interazioni di Copper
- Copper + Omadacycline Moderata
- Copper + Penicillamine Moderata
- Copper + Sarecycline Moderata
- Ascorbic acid + Copper Minore
- Baloxavir marboxil + Copper Minore
- Copper + Vitamin c Minore
Altre interazioni di Trientine
- Calcium + Trientine Moderata
- Carbonyl iron + Trientine Moderata
- Ferrous fumarate + Trientine Moderata
- Ferrous gluconate + Trientine Moderata
- Ferrous sulfate + Trientine Moderata
- Iron + Trientine Moderata
Domande frequenti
Can I take Copper with Trientine?
MediHelp rates the interaction as moderate. Copper and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Trientine chelates copper and promotes its elimination, which is the intended therapeutic effect in Wilson's disease. Copper supplementation would oppose this, and excessive treatment can cause copper deficiency.
How serious is the interaction between Copper and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with trientine for Wilson's disease. Monitor serum and urinary copper and watch for over-treatment such as anemia.
What other medicines interact with Copper?
MediHelp also lists interactions of Copper with, for example, Omadacycline, Penicillamine, Sarecycline. The full list is on the Copper page.
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