Interazioni tra farmaci
Carbonyl iron + Trientine
Gravità: Moderata
Carbonyl iron and Trientine: moderate interaction.
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Sintesi
Oral iron and trientine chelate each other in the gut, reducing absorption of both and possibly weakening copper removal in Wilson disease. Iron-trientine complexes may also irritate the gut.
Cosa significa questa interazione in parole semplici
Carbonyl iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Trientine belongs to Miscellaneous.
Perché avviene
Trientine chelates iron in the gastrointestinal tract, forming poorly absorbed complexes.
Cosa fare
Give iron at least 2 hours apart from trientine. Monitor copper and iron indices.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderata
- Baloxavir marboxil + Carbonyl iron Moderata
- Calcium acetate + Carbonyl iron Moderata
- Calcium carbonate + Carbonyl iron Moderata
- Calcium + Carbonyl iron Moderata
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderata
Altre interazioni di Trientine
- Calcium + Trientine Moderata
- Copper + Trientine Moderata
- Ferrous fumarate + Trientine Moderata
- Ferrous gluconate + Trientine Moderata
- Ferrous sulfate + Trientine Moderata
- Iron + Trientine Moderata
Domande frequenti
Can I take Carbonyl iron with Trientine?
MediHelp rates the interaction as moderate. Carbonyl iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron and trientine chelate each other in the gut, reducing absorption of both and possibly weakening copper removal in Wilson disease. Iron-trientine complexes may also irritate the gut.
How serious is the interaction between Carbonyl iron and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give iron at least 2 hours apart from trientine. Monitor copper and iron indices.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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