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Interazioni tra farmaci

Cyclosporine + Human papillomavirus vaccine

Gravità: Moderata

Cyclosporine and Human papillomavirus vaccine: moderate interaction.

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Sintesi

Cyclosporine suppresses T-cell function and may blunt the antibody response to HPV vaccination. Reduced immunogenicity could leave the patient inadequately protected.

Cosa significa questa interazione in parole semplici

Cyclosporine and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Livello di evidenza: Moderate

Perché avviene

Calcineurin inhibition suppresses T-cell-dependent immune responses to the vaccine.

Cosa fare

Where feasible, complete vaccination at least 2 weeks before starting cyclosporine. If vaccinated during therapy, consider antibody assessment or revaccination once immunosuppression is reduced.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Cyclosporine with Human papillomavirus vaccine?

MediHelp rates the interaction as moderate. Cyclosporine and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine suppresses T-cell function and may blunt the antibody response to HPV vaccination. Reduced immunogenicity could leave the patient inadequately protected.

How serious is the interaction between Cyclosporine and Human papillomavirus vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where feasible, complete vaccination at least 2 weeks before starting cyclosporine. If vaccinated during therapy, consider antibody assessment or revaccination once immunosuppression is reduced.

What other medicines interact with Human papillomavirus vaccine?

MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.

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