Interazioni tra farmaci
Droperidol + Sotalol
Gravità: Controindicata
Droperidol and Sotalol: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Both drugs prolong the QT interval, and combined use raises the risk of torsades de pointes and sudden cardiac death. Droperidol carries a boxed warning for QT prolongation, and sotalol itself has a high intrinsic proarrhythmic risk.
Cosa significa questa interazione in parole semplici
Droperidol and Sotalol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive blockade of cardiac potassium channels (hERG/IKr) causing delayed repolarization and QT prolongation.
Cosa fare
Avoid the combination; choose a non-QT-prolonging antiemetic or sedative such as ondansetron alternatives with lower risk only after ECG assessment. If unavoidable, use continuous ECG monitoring and correct potassium and magnesium first.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Droperidol e Sotalol, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Sotalol
- Arsenic trioxide + Sotalol Controindicata
- Artemether / lumefantrine + Sotalol Controindicata
- Disopyramide + Sotalol Controindicata
- Dofetilide + Sotalol Controindicata
- Dronedarone + Sotalol Controindicata
- Eliglustat + Sotalol Controindicata
Domande frequenti
Can I take Droperidol with Sotalol?
MediHelp rates the interaction as contraindicated. Droperidol and Sotalol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, and combined use raises the risk of torsades de pointes and sudden cardiac death. Droperidol carries a boxed warning for QT prolongation, and sotalol itself has a high intrinsic proarrhythmic risk.
How serious is the interaction between Droperidol and Sotalol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; choose a non-QT-prolonging antiemetic or sedative such as ondansetron alternatives with lower risk only after ECG assessment. If unavoidable, use continuous ECG monitoring and correct potassium and magnesium first.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
