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Interazioni tra farmaci

Etanercept + Measles mumps and rubella vaccine live

Gravità: Controindicata

Etanercept and Measles mumps and rubella vaccine live: contraindicated interaction.

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Sintesi

MMR contains live attenuated viruses that may replicate excessively in patients receiving TNF blockade. This raises the risk of disseminated vaccine-strain infection. The vaccine response may also be impaired.

Cosa significa questa interazione in parole semplici

Etanercept and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Moderate

Perché avviene

TNF inhibition weakens immune control of live attenuated viruses.

Cosa fare

Do not give MMR during etanercept treatment. Vaccinate at least 4 weeks before starting etanercept, or defer until after drug discontinuation and washout.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Etanercept with Measles mumps and rubella vaccine live?

MediHelp rates the interaction as contraindicated. Etanercept and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR contains live attenuated viruses that may replicate excessively in patients receiving TNF blockade. This raises the risk of disseminated vaccine-strain infection. The vaccine response may also be impaired.

How serious is the interaction between Etanercept and Measles mumps and rubella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give MMR during etanercept treatment. Vaccinate at least 4 weeks before starting etanercept, or defer until after drug discontinuation and washout.

What other medicines interact with Etanercept?

MediHelp also lists interactions of Etanercept with, for example, Bcg vaccine live, Golimumab, Measles mumps and rubella vaccine. The full list is on the Etanercept page.

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