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Interazioni tra farmaci

Golimumab + Measles mumps rubella and varicella vaccine live

Gravità: Controindicata

Golimumab and Measles mumps rubella and varicella vaccine live: contraindicated interaction.

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Sintesi

This live attenuated combination vaccine could cause disseminated vaccine-strain infection in patients immunosuppressed by golimumab, and the immune response may be diminished.

Cosa significa questa interazione in parole semplici

Golimumab and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Moderate

Perché avviene

TNF-alpha blockade impairs immune control of replicating live attenuated viruses.

Cosa fare

Avoid during golimumab therapy; vaccinate at least 4 weeks before starting if possible and follow guidelines for timing after stopping.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Golimumab with Measles mumps rubella and varicella vaccine live?

MediHelp rates the interaction as contraindicated. Golimumab and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine could cause disseminated vaccine-strain infection in patients immunosuppressed by golimumab, and the immune response may be diminished.

How serious is the interaction between Golimumab and Measles mumps rubella and varicella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during golimumab therapy; vaccinate at least 4 weeks before starting if possible and follow guidelines for timing after stopping.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

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