Interazioni tra farmaci
Bcg vaccine live + Golimumab
Gravità: Controindicata
Bcg vaccine live and Golimumab: contraindicated interaction.
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Sintesi
BCG vaccine contains live attenuated mycobacteria. In golimumab-treated patients, impaired granuloma function may allow disseminated BCG infection.
Cosa significa questa interazione in parole semplici
Bcg vaccine live and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
TNF is essential for granuloma formation and mycobacterial containment, so its blockade permits BCG dissemination.
Cosa fare
Do not give BCG during golimumab therapy. If needed, vaccinate at least 4 weeks before starting treatment.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Golimumab
- Etanercept + Golimumab Controindicata
- Golimumab + Influenza virus vaccine quadrivalent intranasal Controindicata
- Golimumab + Measles mumps and rubella vaccine Controindicata
- Golimumab + Measles mumps and rubella vaccine live Controindicata
- Golimumab + Measles mumps rubella and varicella vaccine live Controindicata
- Golimumab + Measles vaccine Controindicata
Domande frequenti
Can I take Bcg vaccine live with Golimumab?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG vaccine contains live attenuated mycobacteria. In golimumab-treated patients, impaired granuloma function may allow disseminated BCG infection.
How serious is the interaction between Bcg vaccine live and Golimumab?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during golimumab therapy. If needed, vaccinate at least 4 weeks before starting treatment.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Etanercept, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Golimumab page.
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