Interazioni tra farmaci
Ifosfamide + Measles mumps rubella and varicella vaccine live
Gravità: Controindicata
Ifosfamide and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
MMRV vaccine contains live attenuated viruses, which can replicate without control in a patient immunosuppressed by ifosfamide. This can lead to disseminated vaccine-virus disease, and the vaccine response is also reduced.
Cosa significa questa interazione in parole semplici
Ifosfamide and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Chemotherapy-induced immunosuppression allows unchecked replication of live attenuated virus and impairs the vaccine response.
Cosa fare
Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends, subject to recovery of immune function. Give live vaccines at least 4 weeks before starting chemotherapy when possible.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Controindicata
- Ifosfamide + Measles mumps and rubella vaccine Controindicata
- Ifosfamide + Measles mumps and rubella vaccine live Controindicata
- Ifosfamide + Measles vaccine Controindicata
- Ifosfamide + Rotavirus oral vaccine live Controindicata
- Ifosfamide + Rubella vaccine Controindicata
Domande frequenti
Can I take Ifosfamide with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMRV vaccine contains live attenuated viruses, which can replicate without control in a patient immunosuppressed by ifosfamide. This can lead to disseminated vaccine-virus disease, and the vaccine response is also reduced.
How serious is the interaction between Ifosfamide and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends, subject to recovery of immune function. Give live vaccines at least 4 weeks before starting chemotherapy when possible.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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