Interazioni tra farmaci
Ifosfamide + Rotavirus oral vaccine live
Gravità: Controindicata
Ifosfamide and Rotavirus oral vaccine live: contraindicated interaction.
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Sintesi
Rotavirus vaccine contains live attenuated virus, which could replicate excessively in a patient immunosuppressed by ifosfamide. This raises the risk of prolonged vaccine-virus gastrointestinal infection, and the vaccine response may be reduced.
Cosa significa questa interazione in parole semplici
Ifosfamide and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Chemotherapy-induced immunosuppression allows unchecked replication of live attenuated virus and impairs the vaccine response.
Cosa fare
Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends. Seek specialist advice if an infant is exposed through a treated household member.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Controindicata
- Ifosfamide + Measles mumps and rubella vaccine Controindicata
- Ifosfamide + Measles mumps and rubella vaccine live Controindicata
- Ifosfamide + Measles mumps rubella and varicella vaccine live Controindicata
- Ifosfamide + Measles vaccine Controindicata
- Ifosfamide + Rubella vaccine Controindicata
Domande frequenti
Can I take Ifosfamide with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Ifosfamide and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rotavirus vaccine contains live attenuated virus, which could replicate excessively in a patient immunosuppressed by ifosfamide. This raises the risk of prolonged vaccine-virus gastrointestinal infection, and the vaccine response may be reduced.
How serious is the interaction between Ifosfamide and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends. Seek specialist advice if an infant is exposed through a treated household member.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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