Interazioni tra farmaci
Insulin degludec-insulin aspart + Megestrol
Gravità: Moderata
Insulin degludec-insulin aspart and Megestrol: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Megestrol has glucocorticoid-like activity and can cause hyperglycemia, worsening diabetes control and increasing insulin requirements. Effects are more evident at the higher doses used for appetite stimulation.
Cosa significa questa interazione in parole semplici
Insulin degludec-insulin aspart and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin degludec-insulin aspart belongs to Endocrine; Megestrol belongs to Oncology.
Perché avviene
Progestogen with glucocorticoid activity that induces insulin resistance, opposing insulin action.
Cosa fare
Monitor blood glucose regularly during megestrol therapy and increase the insulin dose as needed. Reduce the insulin dose again when megestrol is stopped.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Insulin degludec-insulin aspart e Megestrol, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 7 giorni sul web. Nessuna carta.
Altre interazioni di Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Maggiore
- Clozapine + Insulin degludec-insulin aspart Maggiore
- Diazoxide + Insulin degludec-insulin aspart Maggiore
- Ethanol + Insulin degludec-insulin aspart Maggiore
- Insulin degludec-insulin aspart + Mecasermin Maggiore
- Insulin degludec-insulin aspart + Pioglitazone Maggiore
Altre interazioni di Megestrol
- Dofetilide + Megestrol Controindicata
- Insulin degludec / insulin aspart + Megestrol Moderata
- Insulin degludec-liraglutide + Megestrol Moderata
- Insulin degludec + Megestrol Moderata
- Insulin inhaled + Megestrol Moderata
- Mavacamten + Megestrol Moderata
Domande frequenti
Can I take Insulin degludec-insulin aspart with Megestrol?
MediHelp rates the interaction as moderate. Insulin degludec-insulin aspart and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Megestrol has glucocorticoid-like activity and can cause hyperglycemia, worsening diabetes control and increasing insulin requirements. Effects are more evident at the higher doses used for appetite stimulation.
How serious is the interaction between Insulin degludec-insulin aspart and Megestrol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose regularly during megestrol therapy and increase the insulin dose as needed. Reduce the insulin dose again when megestrol is stopped.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
