Interazioni tra farmaci
Levothyroxine + Sucroferric oxyhydroxide
Gravità: Moderata
Levothyroxine and Sucroferric oxyhydroxide: moderate interaction.
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Sintesi
Iron-based phosphate binders can bind oral levothyroxine in the gut and reduce its absorption, potentially raising TSH. Parenteral levothyroxine is not affected.
Cosa significa questa interazione in parole semplici
Levothyroxine and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levothyroxine belongs to Endocrine; Sucroferric oxyhydroxide belongs to Genitourinary.
Perché avviene
Iron binds or chelates levothyroxine in the gastrointestinal tract, reducing absorption.
Cosa fare
Give oral levothyroxine at least 4 hours before sucroferric oxyhydroxide. Monitor TSH after starting or changing the binder.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Levothyroxine
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Altre interazioni di Sucroferric oxyhydroxide
Domande frequenti
Can I take Levothyroxine with Sucroferric oxyhydroxide?
MediHelp rates the interaction as moderate. Levothyroxine and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron-based phosphate binders can bind oral levothyroxine in the gut and reduce its absorption, potentially raising TSH. Parenteral levothyroxine is not affected.
How serious is the interaction between Levothyroxine and Sucroferric oxyhydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral levothyroxine at least 4 hours before sucroferric oxyhydroxide. Monitor TSH after starting or changing the binder.
What other medicines interact with Levothyroxine?
MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.
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