Interazioni tra farmaci
Magnesium hydroxide + Ofloxacin
Gravità: Maggiore
Magnesium hydroxide and Ofloxacin: major interaction.
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Sintesi
Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
Cosa significa questa interazione in parole semplici
Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Magnesium hydroxide belongs to Gastrointestinal Tract; Ofloxacin belongs to Anti Bacterial.
Perché avviene
Chelation of ofloxacin by magnesium cations in the gastrointestinal tract reduces absorption.
Cosa fare
Give ofloxacin at least 2 hours before or after magnesium hydroxide.
Cosa chiedere al farmacista
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Altre interazioni di Magnesium hydroxide
- Ciprofloxacin + Magnesium hydroxide Maggiore
- Dolutegravir + Magnesium hydroxide Maggiore
- Gemifloxacin + Magnesium hydroxide Maggiore
- Levofloxacin + Magnesium hydroxide Maggiore
- Magnesium hydroxide + Moxifloxacin Maggiore
- Magnesium hydroxide + Raltegravir Maggiore
Altre interazioni di Ofloxacin
- Ofloxacin + Thioridazine Controindicata
- Adagrasib + Ofloxacin Maggiore
- Amiodarone + Ofloxacin Maggiore
- Amisulpride + Ofloxacin Maggiore
- Anagrelide + Ofloxacin Maggiore
- Arsenic trioxide + Ofloxacin Maggiore
Domande frequenti
Can I take Magnesium hydroxide with Ofloxacin?
MediHelp rates the interaction as major. Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
How serious is the interaction between Magnesium hydroxide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ofloxacin at least 2 hours before or after magnesium hydroxide.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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