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Interazioni tra farmaci

Measles mumps and rubella vaccine live + Oxaliplatin

Gravità: Controindicata

Measles mumps and rubella vaccine live and Oxaliplatin: contraindicated interaction.

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Sintesi

Live MMR vaccine may cause disseminated vaccine-virus infection in patients immunosuppressed by oxaliplatin, and the antibody response may be inadequate.

Cosa significa questa interazione in parole semplici

Measles mumps and rubella vaccine live and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: High

Perché avviene

Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.

Cosa fare

Do not give during oxaliplatin therapy; defer until at least 3 months after chemotherapy ends and immune function has recovered.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Measles mumps and rubella vaccine live with Oxaliplatin?

MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine live and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live MMR vaccine may cause disseminated vaccine-virus infection in patients immunosuppressed by oxaliplatin, and the antibody response may be inadequate.

How serious is the interaction between Measles mumps and rubella vaccine live and Oxaliplatin?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give during oxaliplatin therapy; defer until at least 3 months after chemotherapy ends and immune function has recovered.

What other medicines interact with Oxaliplatin?

MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.

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