Interazioni tra farmaci
Measles mumps rubella and varicella vaccine live + Oxaliplatin
Gravità: Controindicata
Measles mumps rubella and varicella vaccine live and Oxaliplatin: contraindicated interaction.
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Sintesi
Combined live MMRV vaccine may cause disseminated vaccine-strain infection in patients immunosuppressed by oxaliplatin, and immunogenicity is reduced.
Cosa significa questa interazione in parole semplici
Measles mumps rubella and varicella vaccine live and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
Cosa fare
Avoid during oxaliplatin therapy and until immune recovery, generally at least 3 months after stopping. Revaccinate once immunity has recovered.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Controindicata
- Bcg vaccine live + Oxaliplatin Controindicata
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Controindicata
- Measles mumps and rubella vaccine live + Oxaliplatin Controindicata
- Measles mumps and rubella vaccine + Oxaliplatin Controindicata
- Measles vaccine + Oxaliplatin Controindicata
Domande frequenti
Can I take Measles mumps rubella and varicella vaccine live with Oxaliplatin?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combined live MMRV vaccine may cause disseminated vaccine-strain infection in patients immunosuppressed by oxaliplatin, and immunogenicity is reduced.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Oxaliplatin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during oxaliplatin therapy and until immune recovery, generally at least 3 months after stopping. Revaccinate once immunity has recovered.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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