Interazioni tra farmaci
Methoxyflurane + Tetracycline
Gravità: Controindicata
Methoxyflurane and Tetracycline: contraindicated interaction.
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Sintesi
Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
Cosa significa questa interazione in parole semplici
Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive nephrotoxicity from methoxyflurane fluoride metabolites and tetracycline-related renal impairment.
Cosa fare
Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Tetracycline
- Acitretin + Tetracycline Controindicata
- Isotretinoin + Tetracycline Maggiore
- Palovarotene + Tetracycline Maggiore
- Strontium ranelate + Tetracycline Maggiore
- Tetracycline + Tretinoin Maggiore
- Tetracycline + Typhoid vaccine live Maggiore
Domande frequenti
Can I take Methoxyflurane with Tetracycline?
MediHelp rates the interaction as contraindicated. Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
How serious is the interaction between Methoxyflurane and Tetracycline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Isotretinoin, Palovarotene. The full list is on the Tetracycline page.
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