医薬品リファレンス
Apraclonidine
Apraclonidine is a medicine in the class cardiovascular. It is used for ocular hypertension.
- 薬効分類: Cardiovascular
- 効能・効果: ocular hypertension
最終更新日 出典: US FDA label
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要点
- 薬効分類
- Cardiovascular
- 一般的な剤形
- 点滴剤
- 一般的な規格
- 10 mg/ml
- 既知の相互作用
- 6 (併用禁忌: 1 · 重大: 5)
- 商品名
- 2
- 国・市場
- 2
何に使われるか
作用のしくみ
Relatively selective alpha adrenergic agonist without significant membrane stabilizing (local anesthetic) activity; reduces intraocular pressure, predominantly by reducing aqueous formation (mechanism not completely established).
成人の通常用量（添付文書の要約）
Prevention or control of post-surgical IOP elevation after anterior segment laser surgery: 1 drop in the scheduled operative eye one hour before surgery, then a second drop immediately upon completion of the procedure; ophthalmic.
妊娠と授乳
- 妊娠
- Unknown Eye drops: no adequate human studies; embryocidal in rabbits only at high oral doses. Use only if benefit justifies risk. Press on the tear duct after each drop to reduce absorption.
- 授乳
- Unknown Eye drops: unknown if it passes into milk. Label suggests stopping breastfeeding on the day of use. Related clonidine passes into milk; watch the infant for drowsiness. Press on the tear duct after drops.
報告されている副作用
- Conjunctival blanching
- Upper lid elevation
- Mydriasis
- Ocular injection
- Dry mouth
- Headache
禁忌
- Patients receiving monoamine oxidase inhibitor therapy.
- Hypersensitivity to any component of the medication or to clonidine.
注意が必要な方
- For topical ophthalmic use only; not for injection or oral ingestion.
- Cardiovascular collapse requiring intubation and ventilation and other systemic reactions reported in pediatric patients 6 years and younger, including neonates; appropriate clinical monitoring should be in place.
- Patients with exaggerated IOP reductions should be closely monitored.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (6)
- Apraclonidine + Isocarboxazid Contraindicated
- Apraclonidine + Linezolid Major
- Apraclonidine + Phenelzine Major
- Apraclonidine + Rasagiline Major
- Apraclonidine + Selegiline Major
- Apraclonidine + Tranylcypromine Major
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Apraclonidineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- How to give it
- Patient counselling points
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同じ分類のほかの薬剤
よくある質問
What is Apraclonidine used for?
Apraclonidine is a medicine in the class cardiovascular. It is used for Ocular hypertension.
What side effects have been reported with Apraclonidine?
Conjunctival blanching, Upper lid elevation, Mydriasis, Ocular injection, Dry mouth, Headache.
Can Apraclonidine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Eye drops: no adequate human studies; embryocidal in rabbits only at high oral doses. Use only if benefit justifies risk. Press on the tear duct after each drop to reduce absorption. Breastfeeding: Unknown. Eye drops: unknown if it passes into milk. Label suggests stopping breastfeeding on the day of use. Related clonidine passes into milk; watch the infant for drowsiness. Press on the tear duct after drops.
What does Apraclonidine interact with?
MediHelp lists 6 known interactions for Apraclonidine. Contraindicated: 1 · Major: 5. The most serious include Isocarboxazid, Linezolid, Phenelzine.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
