医薬品リファレンス
Dronabinol
Dronabinol is a medicine in the class central nervous system. It is used for nausea & vomiting.
- 薬効分類: Central Nervous System
- 効能・効果: nausea & vomiting
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Central Nervous System
- 一般的な剤形
- カプセル剤, 溶液
- 一般的な規格
- 5 mg, 5 mg/ml
- 既知の相互作用
- 109 (併用禁忌: 2 · 重大: 2 · 中等度: 75 · 軽度: 30)
- 商品名
- 3
- 国・市場
- 2
何に使われるか
作用のしくみ
Dronabinol is an orally active cannabinoid which has complex effects on the CNS, including central sympathomimetic activity. Cannabinoid receptors have been discovered in neural tissues; these receptors may play a role in mediating the effects of dronabinol. Has appetite stimulant effect
成人の通常用量（添付文書の要約）
Oral capsules: 5 mg/m² PO 1-3 hr before and q2-4hr after chemotherapy; may be increased in 2.5 mg/m² increments to 15 mg/m²; not to exceed 4-6 doses/day
妊娠と授乳
- 妊娠
- Unsafe May cause fetal harm; avoid use during pregnancy
- 授乳
- Unsafe Use in nursing mothers is not recommended. Comments: -This drug is absorbed by the nursing infant. There are limited data on the effects on the nursing infant.
報告されている副作用
- Paranoid reaction
- Abnormal thinking
- Somnolence
- Abdominal Pain
- Dizziness
- Euphoria
注意が必要な方
- Avoid concomitant use of drugs with similar effects and monitor for hemodynamic changes; monitor patients for changes in blood pressure, heart rate, and syncope after initiating or increasing the dosage (eg, amphetamines, other sympathomimetic agents, atropine, amoxapine, scopolamine, antihistamines, other anticholinergic agents, amitriptyline, etc
- Seizures and seizure-like activity reported
- New or worsening nausea, vomiting, or abdominal pain can occur during treatment with synthetic delta-9 tetrahydrocannabinol (delta-9-THC), the active ingredient in dronabinol
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (109)
- Cefotetan + Dronabinol Contraindicated
- Disulfiram + Dronabinol Contraindicated
- Dronabinol + Midazolam intranasal Major
- Dronabinol + Zuranolone Major
- Amobarbital + Dronabinol Moderate
- Apalutamide + Dronabinol Moderate
- Atazanavir + Dronabinol Moderate
- Butabarbital + Dronabinol Moderate
- Butalbital + Dronabinol Moderate
- Cannabidiol + Dronabinol Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Dronabinolの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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よくある質問
What is Dronabinol used for?
Dronabinol is a medicine in the class central nervous system. It is used for Nausea & vomiting.
What side effects have been reported with Dronabinol?
Paranoid reaction, Abnormal thinking, Somnolence, Abdominal Pain, Dizziness, Euphoria.
Can Dronabinol be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm; avoid use during pregnancy Breastfeeding: Unsafe. Use in nursing mothers is not recommended. Comments: -This drug is absorbed by the nursing infant. There are limited data on the effects on the nursing infant.
What does Dronabinol interact with?
MediHelp lists 109 known interactions for Dronabinol. Contraindicated: 2 · Major: 2 · Moderate: 75 · Minor: 30. The most serious include Cefotetan, Disulfiram, Midazolam intranasal.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
