医薬品リファレンス
Factor ix
Factor ix is a medicine in the class cardiovascular. It is used for hemophilia b.
- 薬効分類: Cardiovascular
- 効能・効果: hemophilia b
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Cardiovascular
- 一般的な剤形
- 注射剤
- 一般的な規格
- 500 iu, 50 iu/ml
- 既知の相互作用
- 3 (重大: 3)
- 商品名
- 22
- 国・市場
- 3
何に使われるか
作用のしくみ
Mixture of vitamin K-dependent clotting factors; temporarily increases the plasma levels of Factor IX, thus minimizing the hazards of hemorrhage in patients with hemophilia B
成人の通常用量(添付文書の要約)
Number of Factor IX IU required = body weight (kg) x desired increase in plasma Factor IX (%) x 1.2 IU/kg
妊娠と授乳
- 妊娠
- Unknown No studies in pregnant women; most products have no animal studies. Women who carry haemophilia B may need factor IX for bleeding or delivery; use when clearly needed under a haemophilia specialist.
- 授乳
- Unknown No data on milk levels or infant effects. A large protein: milk levels are likely very low and it is probably destroyed in the infant's gut. LactMed: use with caution, especially with a newborn or preterm infant.
報告されている副作用
- Headache
- Dyspnea
- Tachycardia
- Disseminated intravascular coagulation
注意が必要な方
- Thromboembolic events (DVT, PE, thrombotic stroke) as well as DIC reported
- Formation of circulating antibodies inhibiting Factor IX reported
- Factor IX products may partically counteract the effect of warfarin treatment; does NOT include adequate FVII levels to be used to reverse warfarin-induced bleeding
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (3)
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Factor ixの完全なモノグラフ(用量、妊娠・授乳、副作用、警告、すべての相互作用)を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Factor ix used for?
Factor ix is a medicine in the class cardiovascular. It is used for Hemophilia b.
What side effects have been reported with Factor ix?
Headache, Dyspnea, Tachycardia, Disseminated intravascular coagulation.
Can Factor ix be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No studies in pregnant women; most products have no animal studies. Women who carry haemophilia B may need factor IX for bleeding or delivery; use when clearly needed under a haemophilia specialist. Breastfeeding: Unknown. No data on milk levels or infant effects. A large protein: milk levels are likely very low and it is probably destroyed in the infant's gut. LactMed: use with caution, especially with a newborn or preterm infant.
What does Factor ix interact with?
MediHelp lists 3 known interactions for Factor ix. Major: 3. The most serious include Concizumab, Prothrombin complex concentrate human, Tranexamic acid.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。