相互作用
Factor ix + Tranexamic acid
重症度: 重大
Factor ix and Tranexamic acid: major interaction.
最終更新日
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概要
Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.
この相互作用をわかりやすく説明すると
Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Factor ix belongs to Cardiovascular; Tranexamic acid belongs to Cardiovascular.
なぜ起こるのか
Additive procoagulant effects: antifibrinolysis plus factor replacement
対処法
Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Factor ixとTranexamic acidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Tranexamic acidのその他の相互作用
Factor ixのその他の相互作用
よくある質問
Can I take Factor ix with Tranexamic acid?
MediHelp rates the interaction as major. Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.
How serious is the interaction between Factor ix and Tranexamic acid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
