医薬品リファレンス
Levocetirizine
Levocetirizine is a medicine in the class respiratory. It is used for allergic rhinitis.
- 薬効分類: Respiratory
- 効能・効果: allergic rhinitis
最終更新日 出典: US FDA label, CIMA AEMPS (Spain), AEMPS CIMA ficha tecnica (Spanish)
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Respiratory
- 一般的な剤形
- 錠剤, シロップ剤, 溶液, 点滴剤
- 一般的な規格
- 5 mg, 2.5 mg/5 ml, 0.5 mg/ml
- 既知の相互作用
- 44 (中等度: 27 · 軽度: 17)
- 商品名
- 79
- 国・市場
- 5
何に使われるか
作用のしくみ
Levocetirizine selectively inhibits histamine H1 receptors. This action prevents histamine from activating this receptor.
成人の通常用量（添付文書の要約）
Allergic Rhinitis: 5 mg PO qDay in evening. Some patients may respond to 2.5 mg/day
妊娠と授乳
- 妊娠
- Unknown Little data for levocetirizine itself, but large data for cetirizine, its racemic form (over 1,000 pregnancies), show no birth defects or fetal toxicity; animal studies showed no harm. UK label: may be considered in pregnancy if needed. Cetirizine or loratadine are first choices.
- 授乳
- Safe No milk data for levocetirizine; cetirizine passes into milk. LactMed: levocetirizine appears acceptable. High or prolonged doses may cause drowsiness or lower milk supply, especially with pseudoephedrine. Cetirizine is the recommended choice in guidelines.
報告されている副作用
- Fatigue
- Dry mouth
- Nasopharyngitis
- Pharyngitis
禁忌
- Hypersensitivity to levocetirizine or cetirizine
- ESRD (CrCl <10 mL/min) or patients undergoing hemodialysis
- Children aged 6 month to <12 years with renal impairment
注意が必要な方
- May cause CNS depression and impair physical or mental abilities; avoid performin tasks that require mental alertness, including operating heavy machinery or driving
- Urinary retention may occur; use caution in patients at risk of urinary retention, including prostatic hyperplasia and spinal cord injuries
- Use caution in patients with mild to severe renal impairment
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (44)
- Acrivastine + Levocetirizine Moderate
- Asenapine transdermal + Levocetirizine Moderate
- Avapritinib + Levocetirizine Moderate
- Benzhydrocodone / acetaminophen + Levocetirizine Moderate
- Buprenorphine long-acting + Levocetirizine Moderate
- Buprenorphine subdermal implant + Levocetirizine Moderate
- Buprenorphine transdermal + Levocetirizine Moderate
- Clobazam + Levocetirizine Moderate
- Daridorexant + Levocetirizine Moderate
- Diazepam intranasal + Levocetirizine Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Levocetirizineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
関連するクイックリード
よくある質問
What is Levocetirizine used for?
Levocetirizine is a medicine in the class respiratory. It is used for Allergic rhinitis, Urticaria.
What side effects have been reported with Levocetirizine?
Fatigue, Dry mouth, Nasopharyngitis, Pharyngitis.
Can Levocetirizine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Little data for levocetirizine itself, but large data for cetirizine, its racemic form (over 1,000 pregnancies), show no birth defects or fetal toxicity; animal studies showed no harm. UK label: may be considered in pregnancy if needed. Cetirizine or loratadine are first choices. Breastfeeding: Safe. No milk data for levocetirizine; cetirizine passes into milk. LactMed: levocetirizine appears acceptable. High or prolonged doses may cause drowsiness or lower milk supply, especially with pseudoephedrine. Cetirizine is the recommended choice in guidelines.
What does Levocetirizine interact with?
MediHelp lists 44 known interactions for Levocetirizine. Moderate: 27 · Minor: 17. The most serious include Acrivastine, Asenapine transdermal, Avapritinib.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
