相互作用
Benzhydrocodone / acetaminophen + Levocetirizine
重症度: 中等度
Benzhydrocodone / acetaminophen and Levocetirizine: moderate interaction.
最終更新日
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概要
Benzhydrocodone is a prodrug of hydrocodone, an opioid, and sedating antihistamines can add to its CNS and respiratory depression. Excessive drowsiness and impaired psychomotor function may occur.
この相互作用をわかりやすく説明すると
Benzhydrocodone / acetaminophen and Levocetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive CNS depression between an opioid and a sedating antihistamine.
対処法
Use the lowest effective opioid dose and monitor for sedation and respiratory depression; counsel on avoiding driving and alcohol.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Benzhydrocodone / acetaminophenとLevocetirizineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levocetirizineのその他の相互作用
よくある質問
Can I take Benzhydrocodone / acetaminophen with Levocetirizine?
MediHelp rates the interaction as moderate. Benzhydrocodone / acetaminophen and Levocetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benzhydrocodone is a prodrug of hydrocodone, an opioid, and sedating antihistamines can add to its CNS and respiratory depression. Excessive drowsiness and impaired psychomotor function may occur.
How serious is the interaction between Benzhydrocodone / acetaminophen and Levocetirizine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective opioid dose and monitor for sedation and respiratory depression; counsel on avoiding driving and alcohol.
What other medicines interact with Levocetirizine?
MediHelp also lists interactions of Levocetirizine with, for example, Acrivastine, Asenapine transdermal, Avapritinib. The full list is on the Levocetirizine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。