医薬品リファレンス
Patiromer
Patiromer is a medicine in the class miscellaneous. It is used for hyperkalemia.
- 薬効分類: Miscellaneous
- 効能・効果: hyperkalemia
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- ATCコード
- V03AE09
- 一般的な剤形
- 経口懸濁液
- 一般的な規格
- 16.8 g
- 既知の相互作用
- 42 (中等度: 14 · 軽度: 28)
- 商品名
- 3
- 国・市場
- 3
何に使われるか
作用のしくみ
Non-absorbed cation exchange polymer with a calcium-sorbitol counterion. It binds potassium in the GI lumen, increasing fecal potassium excretion and lowering serum potassium.
成人の通常用量（添付文書の要約）
Hyperkalemia: starting dose 8.4 grams orally once daily; increase in increments of 8.4 grams at 1-week or longer intervals based on serum potassium; maximum 25.2 grams once daily
妊娠と授乳
- 妊娠
- Safe Not absorbed from the gut, so maternal use is not expected to expose the fetus. Can be used when needed to treat high potassium.
- 授乳
- Safe Not absorbed by the mother, so it does not reach breast milk. LactMed: no special precautions are needed while breastfeeding.
報告されている副作用
- Constipation
- Hypomagnesemia
- Diarrhea
- Nausea
- Abdominal discomfort
- Flatulence
禁忌
- History of hypersensitivity reaction to Veltassa or any of its components
注意が必要な方
- Avoid in severe constipation, bowel obstruction or impaction, including abnormal post-operative bowel motility disorders; may be ineffective and may worsen GI conditions.
- Binds magnesium in the colon and can cause hypomagnesemia; monitor serum magnesium and consider supplementation if low.
- Not for emergency treatment of life-threatening hyperkalemia because of delayed onset of action.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (42)
- Alogliptin-metformin + Patiromer Moderate
- Canagliflozin-metformin + Patiromer Moderate
- Carvedilol + Patiromer Moderate
- Ciprofloxacin + Patiromer Moderate
- Dapagliflozin-metformin + Patiromer Moderate
- Empagliflozin-metformin + Patiromer Moderate
- Glipizide-metformin + Patiromer Moderate
- Glyburide-metformin + Patiromer Moderate
- Levothyroxine + Patiromer Moderate
- Metformin-pioglitazone + Patiromer Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Patiromerの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
WebでPro+を7日間無料でお試し。カード登録不要。
よくある質問
What is Patiromer used for?
Patiromer is a medicine in the class miscellaneous. It is used for Hyperkalemia.
What side effects have been reported with Patiromer?
Constipation, Hypomagnesemia, Diarrhea, Nausea, Abdominal discomfort, Flatulence.
Can Patiromer be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Not absorbed from the gut, so maternal use is not expected to expose the fetus. Can be used when needed to treat high potassium. Breastfeeding: Safe. Not absorbed by the mother, so it does not reach breast milk. LactMed: no special precautions are needed while breastfeeding.
What does Patiromer interact with?
MediHelp lists 42 known interactions for Patiromer. Moderate: 14 · Minor: 28. The most serious include Alogliptin-metformin, Canagliflozin-metformin, Carvedilol.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
