相互作用
Levothyroxine + Patiromer
重症度: 中等度
Levothyroxine and Patiromer: moderate interaction.
最終更新日
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概要
Patiromer is a non-absorbed polymer that can bind co-administered oral drugs in the gut, reducing levothyroxine absorption. This may lead to under-replacement of thyroid hormone.
この相互作用をわかりやすく説明すると
Levothyroxine and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levothyroxine belongs to Endocrine; Patiromer belongs to Miscellaneous.
なぜ起こるのか
Patiromer binds levothyroxine in the gastrointestinal tract, reducing its absorption.
対処法
Give levothyroxine at least 3 hours before or after patiromer. Monitor TSH when therapy is started or changed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、LevothyroxineとPatiromerの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levothyroxineのその他の相互作用
Patiromerのその他の相互作用
よくある質問
Can I take Levothyroxine with Patiromer?
MediHelp rates the interaction as moderate. Levothyroxine and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patiromer is a non-absorbed polymer that can bind co-administered oral drugs in the gut, reducing levothyroxine absorption. This may lead to under-replacement of thyroid hormone.
How serious is the interaction between Levothyroxine and Patiromer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give levothyroxine at least 3 hours before or after patiromer. Monitor TSH when therapy is started or changed.
What other medicines interact with Levothyroxine?
MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
