医薬品リファレンス
Rocuronium
Rocuronium is a medicine in the class musculoskeletal. It is used for tracheal intubation.
- 薬効分類: Musculoskeletal
- 効能・効果: tracheal intubation
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Musculoskeletal
- 一般的な剤形
- 注射剤, 点滴静注剤
- 一般的な規格
- 50 mg/5 ml, 10 mg/ml, 10 mg
- 既知の相互作用
- 128 (重大: 13 · 中等度: 60 · 軽度: 55)
- 商品名
- 12
- 国・市場
- 4
何に使われるか
作用のしくみ
Nondepolarizing skeletal muscle relaxant; cholinergic receptor antagonist; inhibits depolarization
成人の通常用量（添付文書の要約）
0.45-0.6 mg/kg IV, Maintenance: 0.1-0.2 mg/kg IV repeat PRN
妊娠と授乳
- 妊娠
- Safe Not teratogenic in rats or rabbits; late embryo loss at high doses was put down to lack of ventilation. Widely used for general anaesthesia, including caesarean section. US label: not recommended for rapid sequence induction in caesarean section. Use when needed for anaesthesia.
- 授乳
- Safe Short acting, highly polar and poorly absorbed by mouth, so little reaches milk or the infant; LactMed: no infant effects reported. Breastfeed once the mother has recovered; with several anaesthetic drugs, follow the most restrictive one.
報告されている副作用
- Transient hypotension
- Hypertension
- Apnea
- Dose-related tachycardia
注意が必要な方
- Neuromuscular transmission should be monitored continuously during administration and recovery with the help of a nerve stimulator
- Use caution in patients with significant hepatic disease; if used for rapid sequence induction in patients with ascites
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (128)
- Amikacin + Rocuronium Major
- Bacitracin-neomycin-polymyxin + Rocuronium Major
- Capreomycin + Rocuronium Major
- Clindamycin + Rocuronium Major
- Colistin + Rocuronium Major
- Dexamethasone-tobramycin + Rocuronium Major
- Gentamicin + Rocuronium Major
- Lincomycin + Rocuronium Major
- Magnesium + Rocuronium Major
- Polymyxin b + Rocuronium Major
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Rocuroniumの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Rocuronium used for?
Rocuronium is a medicine in the class musculoskeletal. It is used for Tracheal intubation.
What side effects have been reported with Rocuronium?
Transient hypotension, Hypertension, Apnea, Dose-related tachycardia.
Can Rocuronium be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Not teratogenic in rats or rabbits; late embryo loss at high doses was put down to lack of ventilation. Widely used for general anaesthesia, including caesarean section. US label: not recommended for rapid sequence induction in caesarean section. Use when needed for anaesthesia. Breastfeeding: Safe. Short acting, highly polar and poorly absorbed by mouth, so little reaches milk or the infant; LactMed: no infant effects reported. Breastfeed once the mother has recovered; with several anaesthetic drugs, follow the most restrictive one.
What does Rocuronium interact with?
MediHelp lists 128 known interactions for Rocuronium. Major: 13 · Moderate: 60 · Minor: 55. The most serious include Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
