相互作用
Abrocitinib + Eptifibatide
重症度: 重大
Abrocitinib and Eptifibatide: major interaction.
最終更新日
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概要
Abrocitinib can reduce platelet counts in early treatment and labeling advises against antiplatelet drugs except low-dose aspirin for the first 3 months. Eptifibatide adds potent platelet inhibition, increasing bleeding risk.
この相互作用をわかりやすく説明すると
Abrocitinib and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abrocitinib belongs to Miscellaneous; Eptifibatide belongs to Cardiovascular.
なぜ起こるのか
Additive bleeding risk from GP IIb/IIIa blockade and abrocitinib-associated reduction in platelet count.
対処法
Avoid starting abrocitinib in patients needing eptifibatide during the first 3 months. If unavoidable, monitor platelet counts and bleeding.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AbrocitinibとEptifibatideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eptifibatideのその他の相互作用
Abrocitinibのその他の相互作用
よくある質問
Can I take Abrocitinib with Eptifibatide?
MediHelp rates the interaction as major. Abrocitinib and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Abrocitinib can reduce platelet counts in early treatment and labeling advises against antiplatelet drugs except low-dose aspirin for the first 3 months. Eptifibatide adds potent platelet inhibition, increasing bleeding risk.
How serious is the interaction between Abrocitinib and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid starting abrocitinib in patients needing eptifibatide during the first 3 months. If unavoidable, monitor platelet counts and bleeding.
What other medicines interact with Eptifibatide?
MediHelp also lists interactions of Eptifibatide with, for example, Acalabrutinib, Acetylsalicylic acid, Antithrombin alfa. The full list is on the Eptifibatide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
