相互作用
Antithrombin alfa + Eptifibatide
重症度: 重大
Antithrombin alfa and Eptifibatide: major interaction.
最終更新日
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概要
Together they impair hemostasis via different pathways and increase the risk of serious bleeding.
この相互作用をわかりやすく説明すると
Antithrombin alfa and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive effect of GP IIb/IIIa platelet inhibition and antithrombin-mediated inhibition of coagulation factors.
対処法
Avoid unless clearly indicated; if used, monitor anti-Xa or aPTT, platelets, hemoglobin and bleeding.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Antithrombin alfaとEptifibatideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eptifibatideのその他の相互作用
よくある質問
Can I take Antithrombin alfa with Eptifibatide?
MediHelp rates the interaction as major. Antithrombin alfa and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Together they impair hemostasis via different pathways and increase the risk of serious bleeding.
How serious is the interaction between Antithrombin alfa and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless clearly indicated; if used, monitor anti-Xa or aPTT, platelets, hemoglobin and bleeding.
What other medicines interact with Eptifibatide?
MediHelp also lists interactions of Eptifibatide with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Eptifibatide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
