相互作用
Acetylcysteine + Activated charcoal
重症度: 軽度
Acetylcysteine and Activated charcoal: minor interaction.
最終更新日
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概要
Activated charcoal may adsorb some oral acetylcysteine and reduce its absorption, but studies show this has little effect on its efficacy in acetaminophen overdose. Charcoal use should not delay or preclude acetylcysteine therapy.
この相互作用をわかりやすく説明すると
Acetylcysteine and Activated charcoal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Acetylcysteine belongs to Respiratory; Activated charcoal belongs to Gastrointestinal Tract.
なぜ起こるのか
Adsorption of oral acetylcysteine to activated charcoal in the gut lumen may reduce its absorption.
対処法
Give charcoal when indicated and do not withhold acetylcysteine; use intravenous acetylcysteine or monitor response if oral dosing is used, with doses guided by acetaminophen levels.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AcetylcysteineとActivated charcoalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Acetylcysteineのその他の相互作用
Activated charcoalのその他の相互作用
よくある質問
Can I take Acetylcysteine with Activated charcoal?
MediHelp rates the interaction as minor. Acetylcysteine and Activated charcoal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Activated charcoal may adsorb some oral acetylcysteine and reduce its absorption, but studies show this has little effect on its efficacy in acetaminophen overdose. Charcoal use should not delay or preclude acetylcysteine therapy.
How serious is the interaction between Acetylcysteine and Activated charcoal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give charcoal when indicated and do not withhold acetylcysteine; use intravenous acetylcysteine or monitor response if oral dosing is used, with doses guided by acetaminophen levels.
What other medicines interact with Acetylcysteine?
MediHelp also lists interactions of Acetylcysteine with, for example, Nitroglycerin, Nitroglycerin po, Nitroglycerin rectal. The full list is on the Acetylcysteine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
