相互作用
Acetylsalicylic acid + Mesalamine
重症度: 中等度
Acetylsalicylic acid and Mesalamine: moderate interaction.
最終更新日
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概要
Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.
この相互作用をわかりやすく説明すると
Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Mesalamine belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive effects on renal prostaglandin-dependent perfusion and possible direct tubulointerstitial toxicity of salicylates.
対処法
Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Acetylsalicylic acidとMesalamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Acetylsalicylic acidのその他の相互作用
Mesalamineのその他の相互作用
よくある質問
Can I take Acetylsalicylic acid with Mesalamine?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.
How serious is the interaction between Acetylsalicylic acid and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
