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相互作用

Acrivastine + Butorphanol

重症度: 中等度

Acrivastine and Butorphanol: moderate interaction.

最終更新日

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このページの臨床コンテンツは英語でのみ提供されています。

概要

Acrivastine is a relatively non-sedating antihistamine, but it can cause drowsiness in some patients. Combined with butorphanol, sedation and impaired concentration may be increased.

この相互作用をわかりやすく説明すると

Acrivastine and Butorphanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Acrivastine belongs to Respiratory; Butorphanol belongs to Musculoskeletal.

エビデンスレベル: Low

なぜ起こるのか

Additive central nervous system depression from opioid receptor activity and antihistamine H1 blockade.

対処法

Warn the patient about drowsiness and advise against driving until the response is known. Reduce the butorphanol dose or stop the antihistamine if sedation is excessive.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、AcrivastineとButorphanolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Acrivastine with Butorphanol?

MediHelp rates the interaction as moderate. Acrivastine and Butorphanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Acrivastine is a relatively non-sedating antihistamine, but it can cause drowsiness in some patients. Combined with butorphanol, sedation and impaired concentration may be increased.

How serious is the interaction between Acrivastine and Butorphanol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn the patient about drowsiness and advise against driving until the response is known. Reduce the butorphanol dose or stop the antihistamine if sedation is excessive.

What other medicines interact with Butorphanol?

MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Sodium oxybate, Alfentanil. The full list is on the Butorphanol page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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