相互作用
Adenovirus types 4 and 7 live + Epirubicin
重症度: 併用禁忌
Adenovirus types 4 and 7 live and Epirubicin: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Epirubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The vaccine strains may also replicate more than intended in an immunocompromised patient, leading to vaccine-related infection.
この相互作用をわかりやすく説明すると
Adenovirus types 4 and 7 live and Epirubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Cytotoxic immunosuppression impairs the immune response and permits uncontrolled replication of live attenuated virus.
対処法
Do not give live vaccines during chemotherapy; defer vaccination until immune recovery, usually at least 3 months after treatment ends. Use non-live vaccines where available.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Adenovirus types 4 and 7 liveとEpirubicinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Epirubicinのその他の相互作用
よくある質問
Can I take Adenovirus types 4 and 7 live with Epirubicin?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Epirubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Epirubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The vaccine strains may also replicate more than intended in an immunocompromised patient, leading to vaccine-related infection.
How serious is the interaction between Adenovirus types 4 and 7 live and Epirubicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; defer vaccination until immune recovery, usually at least 3 months after treatment ends. Use non-live vaccines where available.
What other medicines interact with Epirubicin?
MediHelp also lists interactions of Epirubicin with, for example, Belatacept, Cimetidine, Deferiprone. The full list is on the Epirubicin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
