相互作用
Alendronate + Calcium
重症度: 中等度
Alendronate and Calcium: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral calcium binds alendronate in the gut and markedly reduces its absorption. This can make the bisphosphonate less effective for osteoporosis.
この相互作用をわかりやすく説明すると
Alendronate and Calcium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alendronate belongs to Musculoskeletal; Calcium belongs to Gastrointestinal Tract.
なぜ起こるのか
Chelation of alendronate by calcium cations in the gastrointestinal tract reduces absorption.
対処法
Take alendronate first with plain water on an empty stomach and wait at least 30 minutes before any calcium, food or other drinks.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AlendronateとCalciumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Calciumのその他の相互作用
Alendronateのその他の相互作用
よくある質問
Can I take Alendronate with Calcium?
MediHelp rates the interaction as moderate. Alendronate and Calcium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium binds alendronate in the gut and markedly reduces its absorption. This can make the bisphosphonate less effective for osteoporosis.
How serious is the interaction between Alendronate and Calcium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take alendronate first with plain water on an empty stomach and wait at least 30 minutes before any calcium, food or other drinks.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Atazanavir. The full list is on the Calcium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
