相互作用
Calcium + Ceftriaxone
重症度: 併用禁忌
Calcium and Ceftriaxone: contraindicated interaction.
最終更新日 出典: US FDA label
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概要
Ceftriaxone can form insoluble ceftriaxone-calcium precipitates when mixed with or given alongside intravenous calcium. Fatal cases of pulmonary and renal calcium-ceftriaxone precipitation have occurred in neonates. Concurrent use is contraindicated in neonates up to 28 days old, and in older patients the two must not be mixed or given through the same line.
この相互作用をわかりやすく説明すると
Calcium and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Calcium belongs to Gastrointestinal Tract; Ceftriaxone belongs to Anti Bacterial.
なぜ起こるのか
Ceftriaxone binds calcium to form an insoluble salt that precipitates in infusion lines and, in vivo, in lungs and kidneys.
対処法
Do not give ceftriaxone with IV calcium-containing products (including parenteral nutrition) to neonates up to 28 days old.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CalciumとCeftriaxoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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参考文献
- Rocephin (ceftriaxone) Prescribing Information - Contraindications and Warnings — FDA Label
- Ceftriaxone powder for solution for injection/infusion - Summary of Product Characteristics — EMA SmPC
Ceftriaxoneのその他の相互作用
Calciumのその他の相互作用
よくある質問
Can I take Calcium with Ceftriaxone?
MediHelp rates the interaction as contraindicated. Calcium and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ceftriaxone can form insoluble ceftriaxone-calcium precipitates when mixed with or given alongside intravenous calcium. Fatal cases of pulmonary and renal calcium-ceftriaxone precipitation have occurred in neonates. Concurrent use is contraindicated in neonates up to 28 days old, and in older patients the two must not be mixed or given through the same line.
How serious is the interaction between Calcium and Ceftriaxone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give ceftriaxone with IV calcium-containing products (including parenteral nutrition) to neonates up to 28 days old.
What other medicines interact with Ceftriaxone?
MediHelp also lists interactions of Ceftriaxone with, for example, Calcium chloride, Calcium gluconate, Lactated ringer's. The full list is on the Ceftriaxone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
