相互作用
Alendronate + Sucroferric oxyhydroxide
重症度: 中等度
Alendronate and Sucroferric oxyhydroxide: moderate interaction.
最終更新日
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概要
Sucroferric oxyhydroxide is a phosphate binder containing iron that can bind alendronate in the gut. This lowers alendronate absorption and may reduce its efficacy.
この相互作用をわかりやすく説明すると
Alendronate and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alendronate belongs to Musculoskeletal; Sucroferric oxyhydroxide belongs to Genitourinary.
なぜ起こるのか
Binding or chelation of alendronate by iron-containing phosphate binder in the GI tract reduces absorption.
対処法
Take alendronate with plain water at least 1 hour before sucroferric oxyhydroxide, and never at the same time.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、AlendronateとSucroferric oxyhydroxideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
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- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Alendronateのその他の相互作用
Sucroferric oxyhydroxideのその他の相互作用
よくある質問
Can I take Alendronate with Sucroferric oxyhydroxide?
MediHelp rates the interaction as moderate. Alendronate and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sucroferric oxyhydroxide is a phosphate binder containing iron that can bind alendronate in the gut. This lowers alendronate absorption and may reduce its efficacy.
How serious is the interaction between Alendronate and Sucroferric oxyhydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take alendronate with plain water at least 1 hour before sucroferric oxyhydroxide, and never at the same time.
What other medicines interact with Alendronate?
MediHelp also lists interactions of Alendronate with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Alendronate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
