相互作用
Levothyroxine + Sucroferric oxyhydroxide
重症度: 中等度
Levothyroxine and Sucroferric oxyhydroxide: moderate interaction.
最終更新日
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概要
Iron-based phosphate binders can bind oral levothyroxine in the gut and reduce its absorption, potentially raising TSH. Parenteral levothyroxine is not affected.
この相互作用をわかりやすく説明すると
Levothyroxine and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levothyroxine belongs to Endocrine; Sucroferric oxyhydroxide belongs to Genitourinary.
なぜ起こるのか
Iron binds or chelates levothyroxine in the gastrointestinal tract, reducing absorption.
対処法
Give oral levothyroxine at least 4 hours before sucroferric oxyhydroxide. Monitor TSH after starting or changing the binder.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、LevothyroxineとSucroferric oxyhydroxideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levothyroxineのその他の相互作用
Sucroferric oxyhydroxideのその他の相互作用
よくある質問
Can I take Levothyroxine with Sucroferric oxyhydroxide?
MediHelp rates the interaction as moderate. Levothyroxine and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron-based phosphate binders can bind oral levothyroxine in the gut and reduce its absorption, potentially raising TSH. Parenteral levothyroxine is not affected.
How serious is the interaction between Levothyroxine and Sucroferric oxyhydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral levothyroxine at least 4 hours before sucroferric oxyhydroxide. Monitor TSH after starting or changing the binder.
What other medicines interact with Levothyroxine?
MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
