相互作用
Allogeneic cultured keratinocytes and fibroblasts + Silver sulfadiazine
重症度: 中等度
Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Silver sulfadiazine applied to a wound leaves silver ions that are toxic to living cells. This can reduce the viability of the cultured keratinocytes and fibroblasts in the cell-based skin product and impair graft take.
この相互作用をわかりやすく説明すると
Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Local cytotoxicity of silver ions toward cultured human keratinocytes and fibroblasts.
対処法
Do not apply silver sulfadiazine or silver dressings to the site before or at the time of application of the cellular product. Rinse the wound bed thoroughly if silver was previously used.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Allogeneic cultured keratinocytes and fibroblastsとSilver sulfadiazineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Silver sulfadiazineのその他の相互作用
よくある質問
Can I take Allogeneic cultured keratinocytes and fibroblasts with Silver sulfadiazine?
MediHelp rates the interaction as moderate. Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Silver sulfadiazine applied to a wound leaves silver ions that are toxic to living cells. This can reduce the viability of the cultured keratinocytes and fibroblasts in the cell-based skin product and impair graft take.
How serious is the interaction between Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not apply silver sulfadiazine or silver dressings to the site before or at the time of application of the cellular product. Rinse the wound bed thoroughly if silver was previously used.
What other medicines interact with Silver sulfadiazine?
MediHelp also lists interactions of Silver sulfadiazine with, for example, Collagenase, Papain, Trypsin. The full list is on the Silver sulfadiazine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
