医薬品リファレンス
Silver sulfadiazine
Silver sulfadiazine is a medicine in the class anti bacterial. It is used for burns.
- 薬効分類: Anti Bacterial
- 効能・効果: burns
最終更新日
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要点
- 薬効分類
- Anti Bacterial
- 一般的な剤形
- クリーム剤, 吸入器
- 一般的な規格
- 1%, 10 g/1000 g, 10 mg/g
- 既知の相互作用
- 4 (中等度: 4)
- 商品名
- 19
- 国・市場
- 3
何に使われるか
作用のしくみ
Acts on cell membrane and cell wall
成人の通常用量（添付文書の要約）
Burn Wound Infections (2°/3°) (1% cream): Apply to thickness of 1/16 inch qDay-q12hr to burn
妊娠と授乳
- 妊娠
- Unsafe Burn cream: sulfadiazine and some silver are absorbed, more from large burns. No harm in rabbits. US label: contraindicated in women at or near term, as sulfonamides raise the risk of newborn kernicterus. Earlier in pregnancy use only if clearly justified.
- 授乳
- Unknown Not known if it passes into milk; about 10% of the sulfadiazine is absorbed and sulfonamides reach milk. US label: decide whether to stop breastfeeding or the drug (kernicterus). e-lactancia: probably compatible. Avoid with a newborn, preterm, jaundiced or G6PD-deficient infant; never on the breast.
報告されている副作用
- Pain
- Erythema multiforme
- Itching
- Burning
- Necrosis of the skin
禁忌
- Sulfa allergy
- Hypersensitivity
- Pregnant women at term or near term; premature infants, or in infants 2 months or younger
注意が必要な方
- Use caution in G6PD deficiency; hemolysis may occur
- For topical use only; avoid contact with eyes
- Although silver sulfadiazine is minimally absorbed, it reacts with body fluids to release sulfadiazine, which is absorbed and may reach substantial serum concentrations
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (4)
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Silver sulfadiazineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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よくある質問
What is Silver sulfadiazine used for?
Silver sulfadiazine is a medicine in the class anti bacterial. It is used for Burns.
What side effects have been reported with Silver sulfadiazine?
Pain, Erythema multiforme, Itching, Burning, Necrosis of the skin.
Can Silver sulfadiazine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Burn cream: sulfadiazine and some silver are absorbed, more from large burns. No harm in rabbits. US label: contraindicated in women at or near term, as sulfonamides raise the risk of newborn kernicterus. Earlier in pregnancy use only if clearly justified. Breastfeeding: Unknown. Not known if it passes into milk; about 10% of the sulfadiazine is absorbed and sulfonamides reach milk. US label: decide whether to stop breastfeeding or the drug (kernicterus). e-lactancia: probably compatible. Avoid with a newborn, preterm, jaundiced or G6PD-deficient infant; never on the breast.
What does Silver sulfadiazine interact with?
MediHelp lists 4 known interactions for Silver sulfadiazine. Moderate: 4. The most serious include Allogeneic cultured keratinocytes and fibroblasts, Collagenase, Papain.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
