相互作用
Alteplase + Ginko biloba
重症度: 中等度
Alteplase and Ginko biloba: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Ginkgo biloba may impair platelet function, and alteplase carries a substantial bleeding risk. Combining them could theoretically increase hemorrhage, including intracranial bleeding, though clinical evidence is limited.
この相互作用をわかりやすく説明すると
Alteplase and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alteplase belongs to Cardiovascular; Ginko biloba belongs to Gastrointestinal Tract.
なぜ起こるのか
Ginkgolides inhibit platelet-activating factor, adding antiplatelet effects to the thrombolytic action of alteplase.
対処法
Ask about herbal use before thrombolysis and stop ginkgo in elective settings. Monitor closely for bleeding after alteplase if exposure has occurred.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AlteplaseとGinko bilobaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Ginko bilobaのその他の相互作用
Alteplaseのその他の相互作用
よくある質問
Can I take Alteplase with Ginko biloba?
MediHelp rates the interaction as moderate. Alteplase and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba may impair platelet function, and alteplase carries a substantial bleeding risk. Combining them could theoretically increase hemorrhage, including intracranial bleeding, though clinical evidence is limited.
How serious is the interaction between Alteplase and Ginko biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use before thrombolysis and stop ginkgo in elective settings. Monitor closely for bleeding after alteplase if exposure has occurred.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
