相互作用
Ginko biloba + Ketorolac
重症度: 重大
Ginko biloba and Ketorolac: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Ketorolac is a potent NSAID with marked antiplatelet effect and a labeled bleeding warning, and ginkgo biloba adds further antiplatelet activity. Together they may substantially raise the risk of serious bleeding, including gastrointestinal and perioperative hemorrhage.
この相互作用をわかりやすく説明すると
Ginko biloba and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ginko biloba belongs to Gastrointestinal Tract; Ketorolac belongs to Musculoskeletal.
なぜ起こるのか
Additive antiplatelet effects: ginkgolides antagonize platelet-activating factor while ketorolac strongly inhibits COX-1-mediated thromboxane production.
対処法
Avoid ginkgo during ketorolac therapy and stop it before surgery or procedures with bleeding risk. Monitor for bleeding if the combination has been taken.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ginko bilobaとKetorolacの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ginko bilobaのその他の相互作用
Ketorolacのその他の相互作用
よくある質問
Can I take Ginko biloba with Ketorolac?
MediHelp rates the interaction as major. Ginko biloba and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ketorolac is a potent NSAID with marked antiplatelet effect and a labeled bleeding warning, and ginkgo biloba adds further antiplatelet activity. Together they may substantially raise the risk of serious bleeding, including gastrointestinal and perioperative hemorrhage.
How serious is the interaction between Ginko biloba and Ketorolac?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ginkgo during ketorolac therapy and stop it before surgery or procedures with bleeding risk. Monitor for bleeding if the combination has been taken.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Abciximab, Aceclofenac, Acemetacin. The full list is on the Ginko biloba page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
