相互作用
Amlodipine-benazepril + Amphotericin b liposomal
重症度: 中等度
Amlodipine-benazepril and Amphotericin b liposomal: moderate interaction.
最終更新日
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概要
Amphotericin B can cause infusion-related hypotension and nephrotoxicity. Antihypertensives like amlodipine and benazepril may add to hypotension, and ACE inhibitors may worsen renal function in volume-depleted patients.
この相互作用をわかりやすく説明すると
Amlodipine-benazepril and Amphotericin b liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Amphotericin b liposomal belongs to Anti Fungals.
なぜ起こるのか
Additive hypotensive effects, with amphotericin renal toxicity compounding ACE inhibitor effects on glomerular filtration.
対処法
Monitor blood pressure during infusions and check renal function and potassium regularly. Consider holding benazepril if renal function declines.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Amlodipine-benazeprilとAmphotericin b liposomalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amlodipine-benazeprilのその他の相互作用
Amphotericin b liposomalのその他の相互作用
よくある質問
Can I take Amlodipine-benazepril with Amphotericin b liposomal?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Amphotericin b liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause infusion-related hypotension and nephrotoxicity. Antihypertensives like amlodipine and benazepril may add to hypotension, and ACE inhibitors may worsen renal function in volume-depleted patients.
How serious is the interaction between Amlodipine-benazepril and Amphotericin b liposomal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during infusions and check renal function and potassium regularly. Consider holding benazepril if renal function declines.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
