相互作用
Amphotericin b liposomal + Benazepril
重症度: 中等度
Amphotericin b liposomal and Benazepril: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Amphotericin B can cause infusion-related hypotension and renal toxicity, which may be amplified by an ACE inhibitor. Volume depletion and reduced renal function increase the likelihood of problems.
この相互作用をわかりやすく説明すると
Amphotericin b liposomal and Benazepril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Benazepril belongs to Cardiovascular.
なぜ起こるのか
Additive hypotensive effect, with amphotericin nephrotoxicity and ACE inhibitor loss of efferent arteriolar tone compounding renal risk.
対処法
Monitor blood pressure, serum creatinine and potassium during amphotericin therapy and temporarily hold benazepril if hypotension or renal decline develops.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Amphotericin b liposomalとBenazeprilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Benazeprilのその他の相互作用
Amphotericin b liposomalのその他の相互作用
よくある質問
Can I take Amphotericin b liposomal with Benazepril?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Benazepril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause infusion-related hypotension and renal toxicity, which may be amplified by an ACE inhibitor. Volume depletion and reduced renal function increase the likelihood of problems.
How serious is the interaction between Amphotericin b liposomal and Benazepril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum creatinine and potassium during amphotericin therapy and temporarily hold benazepril if hypotension or renal decline develops.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
