相互作用
Amobarbital + Calcium / magnesium / potassium / sodium oxybates
重症度: 併用禁忌
Amobarbital and Calcium / magnesium / potassium / sodium oxybates: contraindicated interaction.
最終更新日
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概要
Oxybate is a potent CNS depressant, and amobarbital is a barbiturate that adds to this effect. Together they can cause profound sedation, respiratory depression, coma and death. Oxybate labeling prohibits use with sedative hypnotics.
この相互作用をわかりやすく説明すると
Amobarbital and Calcium / magnesium / potassium / sodium oxybates are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive pharmacodynamic CNS and respiratory depression.
対処法
Do not combine the two drugs. Use a non-sedating alternative to the barbiturate.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、AmobarbitalとCalcium / magnesium / potassium / sodium oxybatesの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amobarbitalのその他の相互作用
よくある質問
Can I take Amobarbital with Calcium / magnesium / potassium / sodium oxybates?
MediHelp rates the interaction as contraindicated. Amobarbital and Calcium / magnesium / potassium / sodium oxybates are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oxybate is a potent CNS depressant, and amobarbital is a barbiturate that adds to this effect. Together they can cause profound sedation, respiratory depression, coma and death. Oxybate labeling prohibits use with sedative hypnotics.
How serious is the interaction between Amobarbital and Calcium / magnesium / potassium / sodium oxybates?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine the two drugs. Use a non-sedating alternative to the barbiturate.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Doravirine, Elbasvir / grazoprevir, Isavuconazonium. The full list is on the Amobarbital page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
