相互作用
Amoxicillin + Mycophenolate
重症度: 中等度
Amoxicillin and Mycophenolate: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Amoxicillin may lower mycophenolic acid exposure, particularly the late concentration peak, which can reduce immunosuppression. The effect is usually modest.
この相互作用をわかりやすく説明すると
Amoxicillin and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Gut flora alteration reduces deconjugation of mycophenolic acid glucuronide, impairing enterohepatic recirculation.
対処法
Monitor for graft rejection and consider mycophenolic acid level monitoring in high-risk patients during antibiotic therapy.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmoxicillinとMycophenolateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amoxicillinのその他の相互作用
よくある質問
Can I take Amoxicillin with Mycophenolate?
MediHelp rates the interaction as moderate. Amoxicillin and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amoxicillin may lower mycophenolic acid exposure, particularly the late concentration peak, which can reduce immunosuppression. The effect is usually modest.
How serious is the interaction between Amoxicillin and Mycophenolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for graft rejection and consider mycophenolic acid level monitoring in high-risk patients during antibiotic therapy.
What other medicines interact with Amoxicillin?
MediHelp also lists interactions of Amoxicillin with, for example, Methotrexate, Bcg vaccine live, Cholera vaccine. The full list is on the Amoxicillin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
