相互作用
Anastrozole + Ethinyl estradiol-levonorgestrel
重症度: 重大
Anastrozole and Ethinyl estradiol-levonorgestrel: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Anastrozole lowers estrogen levels in postmenopausal breast cancer. Estrogen-containing contraceptives supply exogenous estrogen and may counteract therapy and stimulate hormone-sensitive tumor.
この相互作用をわかりやすく説明すると
Anastrozole and Ethinyl estradiol-levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anastrozole belongs to Oncology; Ethinyl estradiol-levonorgestrel belongs to Endocrine.
なぜ起こるのか
Pharmacodynamic antagonism between exogenous estrogen and aromatase inhibition.
対処法
Avoid estrogen-containing products during anastrozole therapy. Use a non-hormonal contraceptive if contraception is required.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AnastrozoleとEthinyl estradiol-levonorgestrelの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ethinyl estradiol-levonorgestrelのその他の相互作用
- Ethinyl estradiol-levonorgestrel + Fezolinetant 併用禁忌
- Ethinyl estradiol-levonorgestrel + Ombitasvir / paritaprevir / ritonavir and dasabuvir 併用禁忌
- Ethinyl estradiol-levonorgestrel + Tranexamic acid 併用禁忌
- Aminocaproic acid + Ethinyl estradiol-levonorgestrel 重大
- Amobarbital + Ethinyl estradiol-levonorgestrel 重大
- Antithrombin alfa + Ethinyl estradiol-levonorgestrel 重大
Anastrozoleのその他の相互作用
よくある質問
Can I take Anastrozole with Ethinyl estradiol-levonorgestrel?
MediHelp rates the interaction as major. Anastrozole and Ethinyl estradiol-levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anastrozole lowers estrogen levels in postmenopausal breast cancer. Estrogen-containing contraceptives supply exogenous estrogen and may counteract therapy and stimulate hormone-sensitive tumor.
How serious is the interaction between Anastrozole and Ethinyl estradiol-levonorgestrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid estrogen-containing products during anastrozole therapy. Use a non-hormonal contraceptive if contraception is required.
What other medicines interact with Ethinyl estradiol-levonorgestrel?
MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
