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相互作用

Anti-thymocyte + Bcg vaccine live

重症度: 併用禁忌

Anti-thymocyte and Bcg vaccine live: contraindicated interaction.

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概要

Anti-thymocyte globulin causes profound T-cell depletion, so a live attenuated vaccine may cause disseminated infection. The vaccine is also likely to be ineffective in this setting.

この相互作用をわかりやすく説明すると

Anti-thymocyte and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

エビデンスレベル: High

なぜ起こるのか

Profound T-cell immunosuppression allows uncontrolled replication of live attenuated BCG.

対処法

Do not give BCG during or after anti-thymocyte globulin until immune recovery is confirmed by the specialist team. Give it at least several weeks before starting immunosuppression when feasible.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、Anti-thymocyteとBcg vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Anti-thymocyte with Bcg vaccine live?

MediHelp rates the interaction as contraindicated. Anti-thymocyte and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Anti-thymocyte globulin causes profound T-cell depletion, so a live attenuated vaccine may cause disseminated infection. The vaccine is also likely to be ineffective in this setting.

How serious is the interaction between Anti-thymocyte and Bcg vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during or after anti-thymocyte globulin until immune recovery is confirmed by the specialist team. Give it at least several weeks before starting immunosuppression when feasible.

What other medicines interact with Anti-thymocyte?

MediHelp also lists interactions of Anti-thymocyte with, for example, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Anti-thymocyte page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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