相互作用
Arformoterol + Fluticasone-vilanterol
重症度: 重大
Arformoterol and Fluticasone-vilanterol: major interaction.
最終更新日
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概要
Both products contain a long-acting beta2-agonist, so combining them duplicates therapy and increases beta-adrenergic effects such as tachycardia, tremor, hypokalemia and QT prolongation. The risk of arrhythmia is greater than with a single agent.
この相互作用をわかりやすく説明すると
Arformoterol and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Fluticasone-vilanterol belongs to Respiratory.
なぜ起こるのか
Duplicate beta2-adrenergic agonism producing additive cardiovascular and hypokalemic effects.
対処法
Avoid concurrent use of two long-acting beta2-agonists; keep only one LABA and stop the other. Monitor heart rate, ECG and serum potassium if overlap occurs.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ArformoterolとFluticasone-vilanterolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Fluticasone-vilanterolのその他の相互作用
Arformoterolのその他の相互作用
よくある質問
Can I take Arformoterol with Fluticasone-vilanterol?
MediHelp rates the interaction as major. Arformoterol and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both products contain a long-acting beta2-agonist, so combining them duplicates therapy and increases beta-adrenergic effects such as tachycardia, tremor, hypokalemia and QT prolongation. The risk of arrhythmia is greater than with a single agent.
How serious is the interaction between Arformoterol and Fluticasone-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two long-acting beta2-agonists; keep only one LABA and stop the other. Monitor heart rate, ECG and serum potassium if overlap occurs.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
